Long-term outcome after neonatal hypoxic-ischaemic encephalopathy

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Long-term outcome after neonatal hypoxic-ischaemic encephalopathy.

Outcome of full-term infants with neonatal encephalopathy of hypoxic-ischemic origin is often assessed in infancy or early childhood and data on outcome in childhood and adolescence is limited. MRI performed in the neonatal period has made a huge contribution to recognition of different patterns of injury. These different patterns of injury are related to the severity of later motor and cogniti...

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Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy.

There is now a strong evidence base supporting therapeutic hypothermia for infants with moderate or severe neonatal hypoxic ischaemic encephalopathy. Experimental and clinical data indicate that induced hypothermia reduces cerebral hypoxic ischaemic injury and randomized clinical trials in newborns with hypoxic ischaemic encephalopathy confirm improved neurological outcomes and survival at 18 m...

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Survivors with bad outcome after hypoxic-ischaemic encephalopathy: full-term neonates compare unfavourably with children.

UNLABELLED Hypoxic-ischaemic encephalopathy (HIE) is of major importance in neonatal and paediatric intensive care with regard to mortality and long-term morbidity. Our aim was to analyse our data in full-term neonates and children with special regard to withdrawal of life support and bad outcome. PATIENTS All patients with HIE admitted to our unit from 1992-96 were analysed. Criteria for HIE...

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Long-term neurodevelopmental outcome with hypoxic-ischemic encephalopathy.

OBJECTIVES To determine the long-term neurodevelopmental outcome for children after hypoxic-ischemic encephalopathy (HIE) without major disability, and to examine neonatal injury patterns detected on cerebral magnetic resonance imaging (MRI) in relation to later deficits. STUDY DESIGN Prospectively enrolled children with HIE and neonatal cerebral MRI data (n = 68) were examined at a mean age ...

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Early blood glucose profile and neurodevelopmental outcome at two years in neonatal hypoxic-ischaemic encephalopathy

BACKGROUND To examine the blood glucose profile and the relationship between blood glucose levels and neurodevelopmental outcome in term infants with hypoxic-ischaemic encephalopathy. METHODS Blood glucose values within 72 hours of birth were collected from 52 term infants with hypoxic-ischaemic encephalopathy. Hypoglycaemia [< 46.8 mg/dL (2.6 mmol/L)] and hyperglycaemia [> 150 mg/dL (8.3 mmo...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 2010

ISSN: 1359-2998,1468-2052

DOI: 10.1136/adc.2008.148205